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Isomorphism analysis on generalized modules oriented to the distributed parameterized intelligent product

Shasha ZENG, Weiping PENG, Tiaoyu LEI

Frontiers of Mechanical Engineering 2020, Volume 15, Issue 1,   Pages 12-23 doi: 10.1007/s11465-019-0555-9

Abstract: The distributed parameterized intelligent product platform (DPIPP) contains many agents of a product

Keywords： distributed parameterized intelligent product platform     generalized module     isomorphism analysis     productfamily    

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Epidemiological study of a von Hippel-Lindau family in northwest China

Jingyao Zhang, Dapeng Wu, Hong Ai, Jigang Bai, Shunbin Dong, Qinling Yang, Kai Qu, Lei Zhou, Xinsen Xu, Chang Liu

Frontiers of Medicine 2013, Volume 7, Issue 3,   Pages 378-385 doi: 10.1007/s11684-013-0276-0

Abstract: We encountered a large VHL family in northwest China and conducted a systematic screening of the familyFor the preliminary family screening, physical examination and abdomen B ultrasonography were performedA total of 63 lineal descendants in six generations were observed in the family (generations O, A, B,Therefore, follow-up checkups of the family should be focused on younger generations.Proper family screening protocols should be followed for the treatment of patients with VHL disease.

Keywords： von Hippel-Lindau disease     epidemiology     family screening     pancreatic endocrine tumor    

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The Advanced Gun Family——the birth of type 95 (5.8 mm) squad gun family

Duo Yingxian

Strategic Study of CAE 1999, Volume 1, Issue 2,   Pages 57-61

Abstract: So after a short period of cooperated work, a new advanced squad gun family has been developed basedThis guns family were already used to equip the army assigned to Hong Kong in January, 1997 and shall

Keywords： squad gun family     automatic rifle     machine rifle     assault rifle    

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Identification of novel mutations in and in a family with craniofacial microsomia: evidence of digenic

Frontiers of Medicine   Pages 1006-1009 doi: 10.1007/s11684-023-1000-3

Abstract: Identification of novel mutations in and in a family with craniofacial microsomia: evidence of digenic

Keywords： family craniofacial microsomia     Identification novel mutations    

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Family planning technical services in China

Shang-Chun WU

Frontiers of Medicine 2010, Volume 4, Issue 3,   Pages 285-289 doi: 10.1007/s11684-010-0097-3

Abstract: Family planning is a basic state policy in China.Technical services are the key measures for implementing the family planning policy.appropriate contraceptive methods based on the government’s commitment, China has established countrywide family

Keywords： family planning     contraceptive method     service delivery    

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Discussion on the view of feeding patterns in new era’s family planning services

Yan Xiaoqing

Strategic Study of CAE 2014, Volume 16, Issue 5,   Pages 24-30

Abstract: analyzes general reference volume，the impact of feeding-related factors as well as grass-roots demand for familyexplores the scientific and standardized service examination and evaluation system，enhances the grassroots family

Keywords： feeding patterns     statistical analysis     family planning services    

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SUPEROXIDE DISMUTASE FAMILY GENES IN WATERMELON AND THEIR RESPONSES TO DIFFERENT ABIOTIC STRESSES

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 4,   Pages 645-658 doi: 10.15302/J-FASE -2020350

Abstract: Genome-wide analysis of the SOD gene family in various plant species has been conductedbut little is known about this gene family in watermelon (Citrullus lanatus).

Keywords： abiotic stress / expression analysis / phylogeny / SOD / superoxide dismutase / watermelon    

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A novel variant in the gene in a large Chinese family with a unique phenotype of Clouston syndrome

Frontiers of Medicine 2023, Volume 17, Issue 2,   Pages 330-338 doi: 10.1007/s11684-022-0933-2

Abstract: Clouston syndrome (OMIM #129500), also known as hidrotic ectodermal dysplasia type 2, is a rare autosomal dominant skin disorder. To date, four mutations in the GJB6 gene, G11R, V37E, A88V, and D50N, have been confirmed to cause this condition. In previous studies, the focus has been mainly on gene sequencing, and there has been a lack of research on clinical manifestations and pathogenesis. To confirm the diagnosis of this pedigree at the molecular level and summarize and analyse the clinical phenotype of patients and to provide a basis for further study of the pathogenesis of the disease, we performed whole-exome and Sanger sequencing on a large Chinese Clouston syndrome pedigree. Detailed clinical examination included histopathology, hair microscopy, and scanning electron microscopy. We found a novel heterozygous missense variant (c.134G>C:p.G45A) for Clouston syndrome. We identified a new clinical phenotype involving all nail needling pain in all patients and found a special honeycomb hole structure in the patients’ hair under scanning electron microscopy. Our data reveal that a novel variant (c.134G>C:p.G45A) plays a likely pathogenic role in this pedigree and highlight that genetic testing is necessary for the diagnosis of Clouston syndrome.

Keywords： Clouston syndrome     whole exome sequencing     GJB6 gene     novel variant     unique phenotype    

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Oral product input to the GI tract: GIS an oral product performance technology

Gordon L. Amidon, Yasuhiro Tsume

Frontiers of Chemical Science and Engineering 2017, Volume 11, Issue 4,   Pages 516-520 doi: 10.1007/s11705-017-1658-7

Abstract: The patient receives a pharmaceutical product, not a drug.Therefore, it is the product we must optimize for the patients.to assure the safety and efficacy of pharmaceutical products, we need an predictive tool for oral product

Keywords： GIS     in vivo predictive dissolution     ketoconazole     BCS subclassification     supersaturation    

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Panoramic variation analysis of a family with neurodevelopmental disorders caused by biallelic loss-of-function

Frontiers of Medicine doi: 10.1007/s11684-023-1006-x

Abstract: Here, a Pakistani family with parental consanguinity was presented, characterized with severe intellectual

Keywords： neurodevelopmental disorder     autosomal recessive intellectual disability     consanguinity     spastic paraplegia     hearing loss     TMEM141    

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Review of sentiment analysis: An emotional product development view

Frontiers of Engineering Management   Pages 592-609 doi: 10.1007/s42524-022-0227-z

Abstract: Conveying consumers’ specific emotions in new products, referred to as emotional product developmentfeatures by mixing technical product features and consumers’ emotional perceptions.Furthermore, after conceptualizing emotion as Kansei and introducing emotional product development andemotional opinions from online reviews, thus cannot realize data-driven emotional product developmentThis study opens a broad door to aspect-level SA and its integration with emotional product development

Keywords： sentiment analysis     emotion     product development     Kansei Engineering    

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Lean Product Development—Faster, Better … Cleaner?

Geert Letens

Frontiers of Engineering Management 2015, Volume 2, Issue 1,   Pages 52-59 doi: 10.15302/J-FEM-2015007

Abstract: To address this challenge, lean product development has emerged to become the leading improvement methodologyWhile lean product development has its origin in the best practice studies of Japanese car manufacturersand to ground the key aspects of lean product development based on insights from six studies publishedThis demonstrates how better and faster product development can be achieved through the integration of, seems imperative to investigate the integration of lean product development and eco-design principles

Keywords： lean product development     sustainability engineering     responsible design    

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Genetic association between the polymorphism of cytosolic PLA2 gene family and schizophrenia

Qiong YU PhD, Xiang-Fei MENG PhD, Jie-Ping SHI, Ya-Qin YU PhD,

Frontiers of Medicine 2010, Volume 4, Issue 1,   Pages 101-105 doi: 10.1007/s11684-010-0017-6

Abstract: investigate the genetic association between the polymorphism of cytosolic phospholipase A2 (cPLA2) familyreaction (PCR-LDR) was applied to detect the genotype ten single nucleotide polymorphisms (SNPs) of cPLA2 familyOur data suggest that many loci in the cPLA2 family genes may be associated with schizophrenia.

Keywords： schizophrenia     cytosolic phospholipase A2     ligase detection reaction     polymorphism    

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OVEREXPRESSION OF PTRLEA7, A LATE EMBRYOGENESIS ABUNDANT FAMILY GENE FROM PONCIRUS TRIFOLIATA, CONFERS

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 2,

Abstract: This study identified an LEA family gene (PtrLEA7) from Poncirus trifoliata and studied its function
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A family of non-conforming crack front elements of quadrilateral and triangular types for 3D crack problems

Guizhong XIE, Fenglin ZHOU, Hao LI, Xiaoyu WEN, Fannian MENG

Frontiers of Mechanical Engineering 2019, Volume 14, Issue 3,   Pages 332-341 doi: 10.1007/s11465-019-0540-3

Abstract: This study focuses on establishing non-conforming crack front elements of quadrilateral and triangular types for 3D crack problems when the dual boundary element method is applied. The asymptotic behavior of the physical variables in the area near the crack front is fully considered in the construction of the shape function. In the developed quadrilateral and triangular crack front elements, the asymptotic term, which captures the asymptotic behavior of the physical variable, is multiplied directly by the conventional Lagrange shape function to form a new crack front shape function. Several benchmark numerical examples that consider penny-shaped cracks and straight-edge crack problems are presented to illustrate the validity and efficiency of the developed crack front elements.

Keywords： Taylor expansion     crack front elements     stress intensity factors     dual boundary element method    

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Title Author Date Type Operation

Isomorphism analysis on generalized modules oriented to the distributed parameterized intelligent product

Shasha ZENG, Weiping PENG, Tiaoyu LEI

Journal Article

Epidemiological study of a von Hippel-Lindau family in northwest China

Jingyao Zhang, Dapeng Wu, Hong Ai, Jigang Bai, Shunbin Dong, Qinling Yang, Kai Qu, Lei Zhou, Xinsen Xu, Chang Liu

Journal Article

The Advanced Gun Family——the birth of type 95 (5.8 mm) squad gun family

Duo Yingxian

Journal Article

Identification of novel mutations in and in a family with craniofacial microsomia: evidence of digenic

Journal Article

Family planning technical services in China

Shang-Chun WU

Journal Article

Discussion on the view of feeding patterns in new era’s family planning services

Yan Xiaoqing

Journal Article

SUPEROXIDE DISMUTASE FAMILY GENES IN WATERMELON AND THEIR RESPONSES TO DIFFERENT ABIOTIC STRESSES

Journal Article

A novel variant in the gene in a large Chinese family with a unique phenotype of Clouston syndrome

Journal Article

Oral product input to the GI tract: GIS an oral product performance technology

Gordon L. Amidon, Yasuhiro Tsume

Journal Article

Panoramic variation analysis of a family with neurodevelopmental disorders caused by biallelic loss-of-function

Journal Article

Review of sentiment analysis: An emotional product development view

Journal Article

Lean Product Development—Faster, Better … Cleaner?

Geert Letens

Journal Article

Genetic association between the polymorphism of cytosolic PLA2 gene family and schizophrenia

Qiong YU PhD, Xiang-Fei MENG PhD, Jie-Ping SHI, Ya-Qin YU PhD,

Journal Article

OVEREXPRESSION OF PTRLEA7, A LATE EMBRYOGENESIS ABUNDANT FAMILY GENE FROM PONCIRUS TRIFOLIATA, CONFERS

Journal Article

A family of non-conforming crack front elements of quadrilateral and triangular types for 3D crack problems

Guizhong XIE, Fenglin ZHOU, Hao LI, Xiaoyu WEN, Fannian MENG

Journal Article